Crotalaria spectabilis: the pulmonary hypertension plant

  • 146 Pages
  • 4.81 MB
  • English
C. C. Thomas , Springfield, Ill
Crotalaria spectabilis -- Toxico
Statementby J. M. Kay and Donald Heath.
SeriesAmerican lecture series, publication no. 757. A monograph in the Bannerstone Division of American lectures in living chemistry
ContributionsHeath, Donald, joint author.
LC ClassificationsRA1242.C84 K3
The Physical Object
Paginationxiii, 146 p.
ID Numbers
Open LibraryOL5216374M
LC Control Number75083990

Additional Physical Format: Online version: Kay, John Michael. Crotalaria spectabilis: the pulmonary hypertension plant. Springfield, Ill., C.C. Thomas []. Peter G. Anderson, J.

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Thomas Peterson, in The Laboratory Rat (Second Edition), B. Pulmonary Hypertension. Pulmonary hypertension with resulting right ventricular hypertrophy has been produced in rats by administration of Crotalaria spectabilis seeds or extracted monocrotaline pyrrole and by chronic or intermittent exposure to hypobaric pressure.

Pulmonary hypertension with resulting right ventricular hypertrophy has been produced in rats by administration of Crotalaria spectabilis seeds or extracted monocrotaline pyrrole and by chronic or intermittent exposure to hypobaric pressure.

Crotalaria. Author(s): Kay,John Michael; Heath,Donald Title(s): Crotalaria spectabilis, the pulmonary hypertension plant, by J.

Kay and Donald Heath. The pyrrolizidine alkaloid, monocrotaline (MCT), is a plant toxin that causes injury to the vasculature of the lungs and pulmonary hypertension in animals.

To produce lung injury, MCT is bioactivated in the liver by cytochrome P monooxygenases to pyrrolic metabolites which travel via the circulation to the lungs, where they cause injury by Cited Crotalaria spectabilis: the pulmonary hypertension plant book A group of 10 rats was fed on a diet containing powdered Crotalaria spectabilis seeds at a concentration of 1 g per kg diet.

All the animals died after between 36 and 60 days on the diet. All the rats showed increased medial thickness of their pulmonary arteries and an increase in heart weight due to right ventricular hypertrophy. Three rats showed pulmonary by: Treatment of Rattlepods Poisoning in Horses There is no cure for rattlepods poisoning, but supportive treatment can be helpful in horses that only have a small amount (or none) of liver damage.

Treating the conditions caused by complications such as liver disease and pulmonary hypertension can also help. Selected Publications. Kay, J.M. & Heath, D.,Crotalaria spectabilis the pulmonary hypertension plant.

Charles C. Thomas, Springfield, Illinois, In order to induce severe load on predominantly one ventricle, 6-week-old Wistar rats were fed on seeds of the plant Crotalaria spectabilis for 4 weeks. The ensuing pulmonary hypertension resulted in significant hypertrophy of only the right ventricle (52 %).Cited by: 6.

[email protected]: Pulmonary hypertension. In The Heart edited by JW Hurst and RB Logue 3rd ed. New York McGraw-Hill Book Company pp Single or daily doses of seeds of Crotalaria spectabilis and Crotalaria juncea were given to eight young adult goats of both sexes divided randomly in two groups of four goats, e.g.

one group for. The oral administration of Crotalaria spectabilis seeds to young rats induces pulmonary hypertension in them associated with right ventricular hypertrophy and.

Crotalaria juncea a été cultivé comme plante à fibres en Inde depuis avant J.-C. et est une des premières plantes à fibres signalées dans l’histoire. La fibre a été la première introduite en Europe en par l’East India Company, à une période où le jute (Corchorus spp.) était considéré comme une plante à fibres de moindre importance.

Background: Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance, leading to right ventricular failure and death. Recent studies have suggested that chronic inflammatory processes are involved in the pathogenesis of PAH.

Several studies have demonstrated that betaine possesses outstanding anti-inflammatory by: 8. Pulmonary arterial hypertension (PAH) is a multifactorial and severe disease without curative therapies. PAH pathobiology involves altered pulmonary arterial tone, endothelial dysfunction, distal pulmonary vessel remodeling, and inflammation, which could all depend on ion channel activities (K+, Ca2+, Na+ and Cl−).

This review focuses on ion channels in the pulmonary Cited by: This article aims to provide detailed information on Malaysian plants used for treating inflammation. An extensive search on electronic databases including PubMed, Google Scholar, Scopus, and ScienceDirect and conference papers was done to find relevant articles on anti-inflammatory activity of Malaysian medicinal plants.

The keyword search terms used were Cited by: 2. Systemic sclerosis (SSc) is a rare, chronic connective tissue disease affecting the skin, vessels, musculoskeletal system, and internal organs.

Despite advances in pharmacotherapy of organ manifestations and new knowledge about the pathogenesis of SSc, there is still no effective universal treatment of this serious disease. The aim of this chapter is to introduce traditional, Author: Hana Storkanova, Michal Tomcik.

Certain pyrrolizidine alkaloids (e.g., that from Crotalaria spectabilis) pro- duce pulmonary vasculature occlusion and the syndrome of pulmonary hyper- tension in animals, but it is not known whether there is an analogous human response.

Certain pyrrolizidine alkaloids (e.g., that from Crotalaria spectabilis) produce pulmonary vasculature occlusion and the syndrome of pulmonary hypertension in animals, but it is not known whether.

This banner text can have markup. web; books; video; audio; software; images; Toggle navigation. Full text of "Faculty publications and doctoral dissertations" See other formats. For instance, medicinal plant species and plant species have been recorded in Peninsular Malaysia and Sabah, respectively [16, 17].

Inflammation is a response of tissue to cell injury due to pathogens, damaged tissues, or irritants which initiates the chemical signals to heal the afflicted tissue [ 18 ].Cited by: 2.

World Literature on Medicinal Plants from Pankaj Oudhia’s Medicinal Plant Database Oudhia, P. Indian Medicinal Plants used with Ambarvel+Chipurutiga+Dadhittha+Mahapatra and Crotalaria spectabilis Roth for Author: Pankaj Oudhia.

Details Crotalaria spectabilis: the pulmonary hypertension plant PDF

Monocrotaline (MCT) is a toxic membered macrocyclic pyrrolizidine alkaloid (PA) derived from the seeds of the Crotalaria spectabilis plant. It poisons livestock and humans through the ingestion of contaminated grains and other foods. (MCTP) in the liver.

The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy. In Vietnam, the plant is used to expel impurities, to treat syphilis and to treat pulmonary diseases.

Fig. Hypothetical pharmacological properties Cassythia filiformis L alkaloids: the blockade of α1 -adrenoreceptors stimulates urination through relaxation of.

FORUM Plant Resources of Tropical Africa 11(1) Medicinal plants 1 PROTA is an international Foundation involving the following participating institutions: Wageningen University (WU), Plant Sciences Group (PSG), HaarwegP.O. BoxAH Wageningen, Netherlands - Agropolis International (AGROPOLIS), Avenue Agropolis, F Montpellier Cedex 5.

Online Dictionaries: Translation Dictionary English Dictionary French English English French Spanish English English Spanish. #N#Portuguese English English Portuguese German English English German Dutch English English Dutch. Series B, Chemistry, life sciences & earth sciences. 37(3): –Plant Cell Rep.

23(10–11): –Plant Biol. (Stuttg). 8(4): – (Acrid and caustic sap. Rootstalk emetic, emmenagogue and purgative; fresh plant cathartic and anthelmintic; dried pulverized leaves as a dusting powder for unclean wounds, for.

carte plante toxice. download Report. Comments. Transcription. carte plante toxice. POI SONI NG BY PLANTS, MYCOTOXI NS, AND RELATED TOXI NS This page intentionally left blank Poisoning by Plants, Mycotoxins, and Related Toxins Edited by Franklin Riet-Correa Hospital Veterinrio, Universidade Federal de Campina Grande, Patos, Paraba,Brazil J im Pfister USDA-ARS Poisonous Plant Research Laboratory Logan, UtahUSA Ana 5/5(3).

A comprehensive review of chemical constituents, toxicity, and therapeutic values, the book focuses on documentation of the chemical components present and their therapeutic properties. The author begins with a general introduction regarding the geographic advantages for growing varieties of medicinal plants, followed by tables presenting.The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature.

Description Crotalaria spectabilis: the pulmonary hypertension plant EPUB

Monocrotaline is produced for research use. It is used in rat model to investigate human pulmonary hypertension as it offers technical simplicity, reproducibility, and low cost compared with other models of.Lower plant productivity in organic farming mainly related to the poor weed control.

It is widely known, in most cases, that losses caused by weeds exceeded the losses from any category of agricultural pests. Under water-stress condition, weeds can reduce crop yields more than 50% through moisture competition alone. In the light of the.